Gmail (Instead of Outlook)
Gmail has come along way since its beta version several years ago. Now you can get free email from a reliable source that is robust and is interconnected with other well know products such as Google + and Youtube. Also, with each account you can have a virtual drive that you can store information and pull up with any device that has an internet connection. No need to store on your home pc.
Spreadsheet/ClearCheckbook (Instead of Microsoft Money/Quicken)
To help stay organized and efficient you need to track your expenses and income. Some dedicated financial software can be expensive at times. Try these alternatives to keep track of your transactions.
MailChimp (Instead of Aweber)
Your email list can be the lifeblood of your business and you need to be able to respond to your list on a regular basis. Make sure you have a sign up page on your website. Aweber is the most popular program in use, but Mailchimp is perfect for those starting out as it still allows a large number of subscribers.
Gimp (Instead of Adobe Photoshop)
Photoshop has pretty much been the standard image editing tool since... well forever. It is expensive so Gimp is a great alternative for those on a tight budget.
Google Voice (Instead of a regular phone line)
For those of you that don't want to give out your personal or home phone number, you can get a phone number from Google Voice that you can give instead. A Google Voice phone number can be forwarded to your cell phone or home phone. This alone can save you hundreds of dollars a year.
Evernote (Instead of OneNote)
If you are a brainstorming machine and need to keep track of your ideas, try Evernote instead of OneNote. You can store your ideas online by using a simple app. This way you won't forget any of your inspired thoughts.
If you use any or any combination of these programs you could easily save several hundred dollars a year if not more. If you have any suggestions please comment!